个人简介
国家级重点项目主持人、广东“特支计划”青年拔尖人才、首届“光纤传感优秀青年人才”奖获得者
冉洋，教授，博士生导师，广东省第二人民医院兼职特聘教授，入选广东省“特支计划” 青年拔尖人才、“珠江科技新星”、“暨南英才计划杰出人才”、首批点点手机版app“大先生”培养计划。已主持国家自然科学基金3项，其中包括国自然重点项目1项以及其他省市项目共20余项。主要从事光纤生物传感与诊疗以及相关学科交叉研究，在Light Sci. Appl., Nat. Nanotech., Adv. Sci., Adv. Fiber Mater., Chem. Eng. J., Biosens. Bioelectron.发表SCI论文70余篇，累计被引用2000余次，H-index：27。研究成果多次被国外知名专家介绍和正面评述。发表特邀论文5 篇，获得国家发明专利授权7 项，在国际国内上做特邀报告10余次，所指导学生多次在国际国内顶级会议获得最佳论文奖。担任科技部重点研发计划会评专家、国家自然科学基金以及教育部学位论文评审专家；担任Opt. Laser Technol.(IF：4.6，光学权威期刊)副主编，光学工程学会《光纤传感技术及应用蓝皮书》编委，入选光学工程学会首届“光纤传感优秀青年人才”奖。
Researchgate ID: https://www.researchgate.net/profile/Yang_Ran2
ORCID: 0000-0002-9170-7620
主持的科研项目
1. 国家自然科学基金重点项目：面向肿瘤微环境标志物在体检测诊断的光纤传感技术研究，2024-2028，批准号：62335010（在研）。
2. 国家自然科学基金面上项目：面向心肌标志物快速检测的微纳光纤光栅传感器研究，2018-2021，批准号：61775082（已结题）。
3. 国家自然科学基金青年项目：基于双折射微纳光纤光栅的免疫传感器机理与实现研究，2015-2017，批准号：61405074（已结题）。
4. 广州市“珠江科技新星”专项：面向急重症即时检测诊断的微纳光纤光栅传感器研究，2016-2018，批准号：201610010151（已结题）。
5. 广东省自然科学基金自由申请项目：基于倏逝场偏振保持效应的微纳光纤光栅免疫传感器研究，2015-2017，批准号：2015A030313324（已结题）。
6. 点点手机版app交叉研究专项项目（重大项目培育）:光纤肿瘤诊疗一体化技术研究,2020-2022，批准号：21620103 （已结题）。
7. 广州市科技计划“市校联合资助”项目：面向肝原位肿瘤的光纤介入内窥诊疗探针研究，2021-2023，批准号：202102010113（已结题）。
荣誉与奖励
1.广东省“特支计划”青年拔尖人才
2.光学工程学会首届“光纤传感优秀青年人才”奖获得者
3.广州市珠江科技新星
4.暨南英才计划杰出人才培养对象
5.《Optics and Laser Technology》期刊副主编
6.首批点点手机版app“大先生”培养计划入选者
7.暨大科协青年托举计划第一层次培养对象
8.广东省优秀研究生指导教师
9.点点手机版app本科优秀班主任
10.点点手机版app优秀毕业生
代表性论文
1. Y. Zhang, J. Zheng, F. Jin, J. Xiao, N. Lan, Z. Xu, X. Yue, Z. Li, C. Li, D. Cao, Y. Wang, W. Zhong, Y. Ran*, and B.-O. Guan, Fiber-optic drug delivery strategy for synergistic cancer photothermal-chemotherapy, Light: Science & Applications 13, 228(2024).
2. Y. Ran, Z. Xu, M. Chen, W. Wang, Y. Wu, J. Cai, J. Long, Z.-S. Chen, D. Zhang, and B.-O. Guan, Fiber-Optic Theranostics (FOT): Interstitial Fiber-Optic Needles for Cancer Sensing and Therapy, Advanced Science 9, 2200456 (2022).
3. P. Xiao, Z. Xu, D. Hu, L. Liang, L. Sun, J. Li, Y. Ran*, and B.-O. Guan*, Efficiently Writing Bragg Grating in High-Birefringence Elliptical Microfiber for Label-Free Immunosensing with Temperature Compensation, Advanced Fiber Materials 3, 321-330 (2021).
4. H. Xia, W. Zhou, X. Qu, W. Wang, X. Wang, R. Qiao, Y. Zhang, X. Wu, C. Yang, B. Ding, L. Y. Hu, Y. Ran, K. Yu, S. Hu, J. F. Li, H. M. Cheng, H. Qiu, J. Yin, W. Guo, and L. Qiu, Electricity generated by upstream proton diffusion in two-dimensional nanochannels, Nature Nanotechnology 19, 1316-1322 (2024).
5. Z. Li, N. Lan, Z. Cheng, F. Jin, Z. Xu, Y. Zhang, Y. Feng, X. Cai, Y. Ran*, and B.-O. Guan, In vivo fiber-optic fluorescent sensor for real-time pH monitoring of tumor microenvironment, Chemical Engineering Journal 493, 152495 (2024).
6. S. Cao, R. Chen, Q. Yang, X. He, F. Chiavaioli, Y. Ran*, and B. O. Guan, Point-of-care diagnosis of pre-eclampsia based on microfiber Bragg grating biosensor,Biosensors and Bioelectronics 249, 116014 (2024).
7. Y. Ran, J. Long, Z. Xu, Y. Yin, D. Hu, X. Long, Y. Zhang, L. Liang, H. Liang, and B.-O. Guan, Harmonic optical microfiber Bragg grating immunosensor for the accelerative test of cardiac biomarker (cTn-I), Biosensors and Bioelectronics 179, 113081 (2021)
8. T. Liu, L.-L. Liang, P. Xiao, L.-P. Sun, Y.-Y. Huang, Y. Ran*, L. Jin, and B.-O. Guan, A label-free cardiac biomarker immunosensor based on phase-shifted microfiber Bragg grating, Biosensors and Bioelectronics 100, 155-160 (2018).
9. Q. Yang, Y. Hao, Z. Chen, N. Lan, X. He, D. Hu, Z. Xu, L. Liang, D. Cao, J. Guo, Y. Ran*, and B.-O. Guan, Rapid and sensitive detection of cardiac markers using plasmonic gold nanostar-engineered microfiber Bragg grating biosensor, Sensors and Actuators B：Chemical 393, 134248 (2023).
10. Y. Ran, P. Strobbia, V. Cupil-Garcia, T. Vo-Dinh, Fiber-optrode SERS probes using plasmonic silver-coated gold nanostars, Sensors and Actuators B: Chemical 287, 95-101 (2019).
11. P．Strobbia, Y. Ran, B. Crawford, V. Cupil-Garcia, R. Zentella, H-N Wang, T.-P. Sun, and T. Vo-Dinh*, “Inverse Molecular Sentinel-Integrated Fiberoptic Sensor for Direct and in Situ Detection of miRNA Targets, Analytical Chemistry 91, 6345-6352 (2019).
12. Y. Zhang, H. Xia, Q. Yang, Z. Xu, W. Wang, Z. Yuan, Z. Li, S. Cao, B. O. Guan, L. Qiu, and Y.Ran*, A capillary-aided microfiber Bragg grating pH sensor for hydrovoltaic technology, Talanta 274, 125958 (2024).
13. F. Jin, Z. Xu, D. Cao, Y. Ran*, and B.-O. Guan, Fiber-Optic Biosensors for Cancer Theranostics: From in Vitro to in Vivo, Photonic Sensors 14 ,4 (2024).
14. D. Sun, T. Guo, Y. Ran, Y. Y. Huang, and B. O. Guan, In-situ DNA hybridization detection with a reflective microfiber grating biosensor, Biosensors and Bioelectronics 61, 541-546 (2014).
15. X. Yue, R. Lu, Q. Yang, E. Song, H. Jiang, Y. Ran*, and B.-O. Guan*, Flexible Wearable Optical Sensor Based on Optical Microfiber Bragg Grating, Journal of Lightwave Technology 41, 1858-1864 (2023).
16. Y. Wu, M. Chen, J. Cai, Z. Xu, F. Jin, Y. Zhang, W. Wang, Y. Ran*, D. Zhang, and B.-O. Guan, Sensitive and Efficient Fluorescent Fiber-Optic Sensor for In-Situ Hypoxia Detection in Solid Tumor, IEEE Sensors Journal 22, 22646-22653 (2022).
17. Y. Ran, Y. N. Tan, L. P. Sun, S. Gao, J. Li, L. Jin, and B. O. Guan*, 193nm excimer laser inscribed Bragg gratings in microfibers for refractive index sensing, Optics Express 19(19), 18577-18583 (2011).
